A passenger plane with 295 people on board has been shot down as it flew above eastern Ukraine, according to aviation sources.
The Malaysia Airlines plane, which was flying from Amsterdam to Kuala Lumpur, was travelling at an altitude of 10km (6.2 miles) when it was shot down, Russia’s Interfax reported.
The Boeing 777 was brought down by a Buk ground-to-air missile, an adviser to the Ukrainian interior ministry quoted by the news agency said.
The adviser said the 280 passengers and 15 crew members who were on the plane are all believed to have died.
A spokesman for Malaysian Airlines, still reeling from the loss of flight MH370 in March, confirmed it had lost contact with flight MH17, which departed from Amsterdam at 12.14pm local time.
The flight disappeared from radar as it flew over Ukrainian airspace, the spokesman said.